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微小RNA-21与非小细胞肺癌关系的研究新进展 被引量:3

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摘要 miRNA-21,简称miR-21,是miRNA家族的重要成员之一。近来研究发现,miR-21与非小细胞肺癌(non-small cell lung cancer,NSCLC)的预后、转移和诊断等密切相关,推测其可作为NSCLC临床诊治的新靶标。本文就miR-21与非小细胞肺癌的相关研究新进展进行综述。
出处 《现代免疫学》 CAS CSCD 北大核心 2017年第1期59-63,共5页 Current Immunology
基金 国家自然科学基金(31370918) 贵州省高层次创新型人才[黔科合人才(2016)4031号] 贵州省应用基础研究计划重大专项[黔科合J重大字(2015)2003]
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  • 1Barrel DP. MicroRNAs: genomics, biogenesis, mechanism, and function[J]. Cell, 2004, 116(2):281- 97.
  • 2Ambros V. microRNAs~ tiny regulators with great potentia [J]. Cell, 2001, 107:823-826.
  • 3Lagos-Quintana M1, Rauhut R, Lendeckel W, et al, Identifi- cation of novel genes coding for small expressed RNAs [J]. Science, 2001, 294:853-858.
  • 4Cai Xl, Hagedorn CH, Cullen BR. Human microRNAs are processed from capped, polyadenylated transcripts that can also function asmRNAs[J]. RNA, 2004, 10 :1957-1966.
  • 5Drusco A, Nuovo GJ, Zanesi N, et al. MicroRNA profiles discriminate among colon cancer metastasis [J]. PLoS One, 2014, 9:e96670.
  • 6Christensen LL, Holm A, Rantala J, etal. Functional screening identifies miRNAs influencing apoptosis and prolif eration in colorectal cancer [J], PLoS One, 2014, 9:e96767.
  • 7Zhang L, Dong Y, Zhu N, et al. microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorec- talcaneer[J]. Mol Cancer, 2014, 13:124.
  • 8Fang L1, Li H, Wang L, et al. MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression [J]. Onco- target, 2014, 5:2974-2987.
  • 9Tang W, Zhu Y, Gao J, et al. MicroRNA-29a promotes eolorectal cancer metastasis by regulating matrix metallopro- teinase 2 and E-cadherin via KLF4 [J]. Br J Cancer, 2014, 110,450-458.
  • 10Meng F, Henson R, Wehbe-Janek H, et al. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer[J].Gastroenterology, 2007, 133:647-658.

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