集体治疗缓解酒依赖患者焦虑抑郁症状的初步评价

Group psychotherapy on anxiety and depression symptoms in patients with alcohol dependence

目的:初步探讨集体治疗对缓解酒依赖患者焦虑抑郁症状的临床疗效。方法:选取普洱市第二人民医院2014年1月1日-12月31日入院诊断为酒依赖患者,使用焦虑自评量表(SAS)、抑郁自评量表(SDS)及简明精神病量表(BPRS)筛查为伴随焦虑抑郁状态者117例,采用入院先后顺序分为药物联合集体治疗组(干预组,n=89)和单纯药物治疗组(对照组,n=88),两组均给予复方地西泮替代治疗,干预组在此基础上联合集体治疗,观察8周。使用临床疗效总评量表(CGI)评定总体疗效。结果:干预组治疗后SAS、SDS、BPRS、CGI得分均低于治疗前[(21.1±8.3)vs.(65.3±10.2),(35.1±7.5)vs.(73.4±9.2),(20.7±3.5)vs.(51.7±5.6);(4.3±1.0)vs.(5.4±0.6),P<0.01或P<0.05]。对照组治疗前后各量表得分差异均无统计学意义(均P>0.05)。结论:药物治疗基础上的集体治疗在缓解酒依赖患者焦虑抑郁方面优于单纯药物治疗。

Objective：To explore the clinical effect of group psychotherapy on relieving anxiety and depression symptoms in patients with alcohol dependence.Methods：Totally 117 patients with alcohol dependence accompanied with anxiety and depression symptoms were selected from the Second People＇s Hospital of Puer City from 2014 January 1 to December 31.The anxiety and depression symptoms were assessed with the Self-Rating Anxiety Scale（SAS）,Self-Rating Depression Scale（SDS） and Brief Psychiatric Rating Scale（BPRS）.They were divided into drug combined group（intervention group,n = 89） and single drug treatment group（control group,n = 88）.The two groups were administrated diazepam replacement therapy,and the intervention group combined group psychotherapy.Eight weeks later,treatment effect of the two groups were evaluated with the Clinical Global Impression Scale（CGI）.Results：After intervention,the scores of SAS,SDS,BPRS,and CGI in intervention group decreased[（21.1±8.3） vs.（65.3±10.2）,（35.1±3.5） vs.（51.7±5.6）,（4.3±1） vs.（5.4±0.6）,Ps〈0.05].There was no significant difference in above scores between before and after treatment in the control group（Ps〉 0.05）.Conclusion：The effect of group psychotherapy on the basis of medicine may be better than that of single drug therapy on relieving anxiety and depression in patients with alcohol dependence.