摘要
功能性消化不良(functional dyspepsia,FD)被认为是生物因素和社会心理因素复合作用下,引起脑肠轴功能失调的一系列综合反应.胃肠动力障碍与精神情志障碍是导致FD发病的重要因素,脑肠轴功能异常是发病的核心机制.FD的高发病率已引起高度的重视,因此本文综述了FD在发病机制和治疗方面最新的研究进展.
Functional dyspepsia(FD) is considered to be a series of integrated responses to dysfunction of the brain-gut axis caused by a combination of biological factors and socio-psychological factors.Gastrointestinal motility disorder and mental emotional disorder are important factors leading to the development of FD,and abnormal function of the brain-gut axis is the core mechanism of FD pathogenesis.The high incidence of FD has caused a high degree of attention.In this paper,we will review the latest advances in the understanding of the pathogenesis of FD and in its treatment.
出处
《世界华人消化杂志》
CAS
2017年第1期84-90,共7页
World Chinese Journal of Digestology
基金
国家自然科学基金资助项目
No.81360540
甘肃省中医药管理局基金资助项目
Nos.GZK-2012-31
GZK-2013-29
甘肃省科技厅自然基金资助项目
No.1212RJZA081
甘肃省中药药理与毒理学重点实验室基金资助项目
No.ZDSYS-KJ-2013-003~~
关键词
功能性消化不良
脑肠轴
胃肠动力障碍
精神情志障碍
研究进展
Functional dyspepsia
Brain-gut axis
Gastrointestinal motility disorder
Mental emotional disorders
Research progress