基于动态多叶光栅的肿瘤追踪放射治疗技术的研究进展

A review of progress of real-time tumor tracking radiotherapy technology based on dynamic multi-leaf collimator

在胸腹部肿瘤患者的放射治疗中,肿瘤受呼吸及其他生理运动的影响限制了放疗精度的进一步提高。肿瘤追踪放射治疗技术是应对胸腹部肿瘤分次内运动的一个理想方法。本综述简要介绍了动态多叶光栅(DMLC)在肿瘤追踪放射治疗领域的研究进展及应用,包括DMLC追踪方法、DMLC追踪系统的时间迟滞效应,以及DMLC追踪的剂量学验证三个方面。

While radiation treatment to patients with tumors in thorax and abdomen is being performed, further improvement of radiation accuracy is restricted by the tumor intra-fractional motion due to respiration. Real-time tumor tracking radiation is an optimal solution to tumor intra-fractional motion. A review of the progress of real-time dynamic multi-leaf collimator （DMLC） tracking is provided in the present review, including DMLC tracking method, time lag of DMLC tracking system, and dosimetric verification.