肠系膜牵拉综合征的研究进展

Advances on the research of mesenteric traction syndrome

背景 肠系膜牵拉综合征（mesenteric traction syndrome, MTS）在腹部手术中发生率较高，会引起术中低血压和心动过速，对麻醉管理带来一定程度的挑战。 目的 探寻MTS的发生机制和防治措施。 内容 前列环素和组胺参与MTS的发生。非选择性环氧化酶（cyclooxygenase, COX）抑制剂、组胺受体阻滞剂以及血管活性药物在临床上被用于MTS的预防和治疗。 趋向 对MTS发生机制的进一步研究，将有助于筛选MTS的易感人群以及实施更加合理有效的防治措施。

Background Mesenteric traction syndrome（MTS）, a common phenomenon during abdominal surgery, which is manifested as hypotension and tachycardia, make a great challenge to the anesthesiologist on intraoperative management. Objective To elucidate the mechanism of MTS and the strategies of prevention and treatment. Content Prostacyclin and histamine play a key role in MTS. Non-selective cyclooxygenase（COX） inhibitors, histamine receptor blockers, and vasoactive drugs are administered for prevention and treatment of MTS in the clinical practice. Trend Further studies of MTS will help to find out the patients susceptible to MTS and implement more effective strategies for prevention and treatment.