探讨小潮气量通气联合允许性高碳酸血症治疗足月儿重症胎粪吸入综合征

Discussion of Small Tidal Volume Ventilation Combined Permissive Hypercapnia in the Treatment of Term Infant with Severe Meconium Aspiration Syndrome

目的:探讨小潮气量通气联合允许性高碳酸血症治疗足月儿重症胎粪吸入综合征的临床疗效。方法:将医院2015年1月~2016年2月期间诊治的97例足月重症胎粪吸入综合征患儿随机分成两组,观察组(n=48)应用小潮气量通气联合允许性高碳酸血症治疗,对照组(n=49)行传统大潮气量通气治疗,对比两组治疗效果和并发症。结果:(1)观察组并发症发生率低于对照组(P<0.05);(2)观察组呼吸及血气分析指标均优于对照组(P<0.05)。结论:小潮气量通气联合允许性高碳酸血症治疗足月儿重症胎粪吸入综合征的临床效果确切,值得借鉴。

Objective：To investigate the clinical effects of small tidal volume ventilation combined permissive hypercapnia in the treatment of term infant with severe meconium aspiration syndrome.Methods：97cases of full-term infants with severe meconium aspiration syndrome treated in a hospital from January 2015 to February 2016 were randomly divided into two groups.The observation group（n=48）was given small tidal volume ventilation combined permissive hypercapnia treatment,and the control group（n=49）was given traditional tidal volume ventilation therapy,then compared the treatment effects and complications of two groups.Results：（1）The incidence of complications of observation group was lower than that of control group（P〈0.05）;（2）The breathing and blood gas analysis of observation group were better than those of control group（P〈0.05）.Conclusion：Small tidal volume ventilation combined permissive hypercapnia in the treatment of term infant with severe meconium aspiration syndrome has exact effect,which is worthy of reference.