左氧氟沙星治疗耐多药肺结核疗效与安全性的系统评价探讨

System Evaluation of Curative Effect and Security of Levofloxacin in the Treatment of Multi-drug Resistant Tuberculosis

目的:分析研究左氧氟沙星治疗耐多药肺结核疗效与安全性。方法:选取2013年2月~2015年2月在某院接收的耐多药肺结核患者共有164例,随机分为实验组、对照组,对照组采取常规治疗,实验组在此基础之上采取左氧氟沙星治疗,对两组患者的临床疗效和不良反应给予分析研究。结果:实验组患者的治疗效果明显优于对照组,不良反应明显低于对照组,其之间的差异具有统计学意义(P<0.05)。结论:对耐多药肺结核患者采取左氧氟沙星进行治疗,不但可以取得显著的治疗效果,同时不良反应较低,具有安全有效性。

Objective：To analyze the curative effect and security of levofloxacin in the treatment of multidrug resistant tuberculosis.Methods：164cases of multi-drug resistant tuberculosis patients treated in a hospital from February 2013 to February 2015 were selected and randomly divided into experimental group and control group.The control group was given conventional treatment,and the experimental group received levofloxacin treatment based on the control group.Then the clinical curative effect and adverse reactions of two groups were studied and analyzed.Results：The therapeutic effect of experimental group was better than that of control group,and the adverse reactions was significantly lower than that of control group,which the differences were statistically significant（P〈0.05）.Conclusion：The levofloxacin in the treatment of multidrug resistant tuberculosis not only can acquire significant treatment effect,but also reduce the adverse reactions at the same time,with safety and validity.