2010～2015年某三甲医院质子泵抑制药使用分析

Application Analysis of Proton Pump Inhibitors in a Three-A Hospital from 2010 to 2015

目的:了解并分析某三甲医院质子泵抑制药(PPIs)的使用情况,以促进该院PPIs的合理应用。方法:从该院计算机信息管理系统中调取2010~2015年门诊及住院患者所有PPIs的销售记录,并对其销售金额、用药频度(DDDs)、限定日费用(DDC)、年消耗量等指标进行分析。结果:2010~2015年该院PPIs销售金额和DDDs呈上升趋势,销售金额的年均复合增长率为13.84%。6年PPIs注射剂的销售金额及DDDs各占82.2%和29.6%;PPIs口服剂的销售金额及DDDs各占17.8%和70.3%;销售总金额位于前三位的是注射用泮托拉唑钠、注射用兰索美拉唑钠和注射用埃索美拉唑钠。结论:该院PPPs中注射用泮托拉唑钠、注射用兰索拉唑用量相对较大,不排除存在注射剂过度使用的情况。

Objective： To analyze the utilization of proton pump inhibitors （PPIs） in a three-A hospital to promote the rational use. Methods： The sales records of PPIs used for outpatients and inpatients were retrieved from the hospital database from 2010 to 2015, and the consumption sum, DDDs and DDC were analyzed statistically. Results： The consumption sum and DDDs of PPIs in the hospital were increasing, and the compound annual growth rate （CAGR） of consumption sum was 13.84%. The proportion of con- sumption sum and DDDs for PPIs injections respectively was 82.2% and 29.6% in the six years. The proportion of consumption sum and DDDs of oral PPIs respectively was 17.8% and 70.3% in the six years. The top three drugs in the list of consumption sum were pantoprazole, lansoprazole and esomeprazole. Conclusion： The application amounts of pantoprazole sodium for injection and lanso- prazole sodium for injection are relatively large, and the overuse of PPIs for injection can not be excluded.