合肥市40岁以上社区人群代谢综合征的患病现状及危险因素分析

Analysis of prevalence and risk factors of metabolic syndrome in Hefei community population aged over 40

目的了解合肥市社区人群代谢综合征(MS)的患病现状及其相关危险因素。方法针对中国糖尿病与肿瘤发生风险的前瞻性随访研究的基线调查资料,排除部分数据缺失、误差,选取有年龄、性别、既往史、身高、体重、腰臀围、血糖、血脂、血压等具有完整资料的40岁以上人群共9 977例进行分析。代谢综合征诊断标准采用2007年《中国成人血脂异常防治指南》修订定义。将调查对象分为正常组和MS组,采用t检验和χ2检验比较两组之间年龄、性别、血脂、体质指数(BMI)等指标的差异,采用Logistic回归分析MS发病的相关危险因素。结果合肥市40岁以上社区居民MS的粗患病率为27.6%,标化患病率为26.6%。MS患病率随着年龄增加逐渐增高,MS组患者血压、腰臀比、BMI、糖化血红蛋白等指标均较正常人群增高,差异均有统计学意义(P<0.05)。多因素回归分析结果显示年龄、BMI、三酰甘油是MS的独立危险因素,而高密度脂蛋白胆固醇是代谢综合征的保护性因素。结论 MS发病率较高,与多种因素有关,应针对相关危险因素积极采取干预措施,预防疾病发生。

Objective To determine the prevalence and risk factors for metabolic syndrome （MS） in the community population in Hefei. Methods Based on the data collected in the baseline survey and REACTION research, after elimination of miss and errors, a total of 9 977 patients were selected, who were aged ≥40 years with complete data including age, gender, medical history, height, weight, waist-hip ratio, blood sugar, blood lipid and blood pressure. Participants were divided into two groups （normal and MS） , and MS patients were screened by Chinese guidelines on dyslipidemia in adults 2007. Chi-square test and t test were engaged to test for age, sex, blood lipids and body mass index （BMI） differences between the two groups. Logistic regression was served to analyze the risk factors for MS. Results Crude prevalence ratio and standardized prevalence ratio of MS patients in Hefei community populations （age 〉 40 years） were 27.6% and 26.6% , respectively. The prevalence ratio for MS patients increased with aging. The values of blood pressure, waist-hip ratio, BMI and HbAIC were significantly increased in MS group, as compared with the corresponding values in the control group （P 〈 0. 05）. Age, BMI and triglyceride were independent risk factors for MS. High-density lipoprotein was a protection factor for MS. Conclusion High prevalence ratio for MS is associated with muhiple factors. Strategies aimed at MS-related risk factors may be bene-ficial to prevent against MS.