男性冠状动脉慢血流现象的危险因素分析

Riskfactor analysis of slow coronary flow phenomenon in male patients

目的:探讨男性冠状动脉慢血流现象(SCF)相关的危险因素。方法:选择我院因胸痛怀疑冠心病行冠状动脉造影显示心外膜下冠状动脉无明显病变的男性患者123例,按照是否发生SCF分为:SCF组(69例)和正常组(54例)。回顾性分析两组病历资料,采用Logistic回归分析对男性SCF的危险因素进行分析。结果:与正常组比较,SCF组人体质量指数[BMI,(24.01±1.57)kg/m^2比(27.06±3.40)kg/m^2]、血红蛋白[(145.79±9.63)g/L比(150.00±11.84)g/L]、红细胞压积[(0.43±0.03)L/L比(0.45±0.06)L/L]均明显升高(P均<0.05)。Logistic回归分析表明,BMI(OR=1.373,95%CI 1.146~1.645,P=0.001)、血红蛋白(OR=1.037,95%CI 1.000~1.176,P=0.048)是男性SCF的独立危险因素。结论:人体质量指数、血红蛋白浓度的升高是男性冠状动脉慢血流的独立危险因素,必须进行相应的防治,以改善预后。

Objective： To explore risk factors for slow coronary flow （SCF） phenomenon in male patients. Methods： A total of 123 male patients, who were suspecting coronary heart disease because of chest pain, then coronary angiography indicated there was no significant lesion in epicardial coronary arteries, were selected. According to presence of SCF or not, they were divided into SCF group （n = 69） and normal group （n = 54）. Case data of two groups were retrospectively analyzed, and Logistic regression analysis was use to analyze risk factors for male SCF. Results： Compared with normal group, there were significant rise in body mass index [BMI, （24. 01 ± 1.57） kg/m2 vs. （27. 06 ±3.40） kg/m2 ], hemoglobin level [ （145. 79 ± 9.63） g/L vs. （150.00 ±11.84） g/L] and hematocrit [ （0.43± 0.03） L/L vs. （0.45 ± 0. 06） L/L] in SCF group, P〈0.05 all. Logistic regression analysis indicated that BMI （OR= 1. 373, 95% CI 1. 146-1. 645, P = 0. 001） and hemoglobin （OR = 1. 037, 95 % CI 1. 000-1. 176, P = 0. 048） were independent risk factors for male SCF. Conclusion： Elevated body mass index and hemoglobin level are independent risk factors for slow coronary flow in male patients, so corresponding preventive measures must be carried out to improve prognosis.