姜黄素分子印迹聚合物的制备与表征及其吸附性能的研究

Preparation and characterization of curcumin molecularly imprinted polymers and the study of its adsorption properties

目的制备姜黄素的分子印迹聚合物(MIP)。方法以姜黄素为模板分子、乙二醇二甲基丙烯酸酯为交联剂、偶氮二异丁腈为引发剂,模板分子-功能单体-交联剂的摩尔比为1∶4∶20;采用本体聚合法,通过优化条件获得了对姜黄素有特异选择性吸附的MIP;采用红外光谱仪、扫描电镜和热重分析仪对聚合物进行结构表征,并研究MIP的吸附性能。结果制备MIP的最优条件是以甲基丙烯酸为功能单体,溶剂为丙酮;该聚合物的印迹因子为1.27,符合拟二级动力学模型(r2=0.9970)。结论制备的MIP可用于分离、纯化和富集姜黄素。

OBJECTIVE To prepare curcumin molecularly imprinted polymer（MIP）. METHODS MIP of curcumin with recognition properties were prepared by bulk polymerization method using eurcumin as templates, ethylene dimethaerylate as crosslinker and azobisisobutyronitrile as initiators under the optimized conditions. The structure of the polymer was characterized by infrared spectroscopy, scanning electron microscope and thermogravimetrie analyzer. The adsorption experiment was used to investigate the adsorption properties of MIP to template molecular. RESULTS The optimized conditions were using methacrylic acid as functional monomers and acetone as the solvent. The imprinting factor of MIP was 1.27 and the adsorption behavior obeyed pseudo - second - order kinetic model（ r^2 = 0. 9970）. CONCLUSION The imprinted polymer can be applied to separate, purify and enrich curcumin.