摘要
以甲醇(1)和月桂酸(2)为原料,碘和对甲苯磺酸协同催化合成了月桂酸甲酯(3),其结构经IR确证。考察了催化剂、反应时间、反应温度和物料比r[n(1)∶n(2)]对3产率的影响。结果表明:在最优反应条件(2 10mmol,r=15∶1,3 mol%TsOH,6 mol%I2,于60℃反应90 min)下,3产率93.5%。
Methyl laurate （3） was synthesized using MeOH （ 1 ） and lauric acid （2） as the materials and TsOH-I2 as the cooperative catalyst. The structure was confirmed by IR. Effects of catalysts, reaction time, temperature and material mole ratio [ r = n （ 1 ） ： n （2） ] on yield of 3 were investigated. The results indicated that under the optimum reaction conditions（2 10mmol, r = 15 ： 1, 3 mol%TsOH, 6mol% I2, reaction at 60 ℃ for 90 min）, the yield of 3 was 93.5%.
作者
王琳琳
杜莹
吴小云
罗世霞
尹晓刚
WANG Lin-lin DU Ying WU Xiao-yun LUO Shi-xia YIN Xiao-gang(Key Eaboratory of Functional Materials Chemistry of Guizhou Province, School of Chemistry and Materials Science, Guizhou Normal University, Guiyang 550001, China)
出处
《合成化学》
CAS
CSCD
2017年第2期144-147,共4页
Chinese Journal of Synthetic Chemistry
基金
国家自然科学基金资助项目(21362006)
贵州省科技合作项目(黔科合LH字[2016]7218)
贵州省科技厅科技支撑项目(黔科合支撑[2016]2311)
