额顶骨巨大胆脂瘤1例（英文）

A case report for giant cholesteatoma occurred in fronto-parietal bone

胆脂瘤是一类主要由复层鳞状上皮细胞组成,少见的具有侵蚀性的先天性良性肿瘤。此肿瘤常成隐匿性起病,可侵蚀颅骨,因生长缓慢,可长期无明显症状,不易被发现。颅骨内起源的胆脂瘤大多发生于颞骨、中颅窝区域。1例误诊为皮脂腺囊肿伴感染的胆脂瘤患者,在中南大学湘雅二医院行手术治疗并病检确诊。该患者起病不典型,病变部位不典型,病变体积大,国内外罕有此部位巨大胆脂瘤占位的报道。

Cholesteatoma is a destructive and expanding growth benign tumor, mainly consisting of stratified squamous epithelium. It possesses the capacity of eroding bone and can exist in a nonaggressive state, remaining undetected for years. Once cholesteatoma appeared, it grows relentlessly and threats to invade intra-temporal structures. Most cholesteatomas occurred in the petrous bone and also affected the labyrinth and middle cranial fossa. Here, we report a preliminary wrongly- diagnosed case. The patient was wrongly diagnosed as ＂sebaceous cyst with infection＂ by local hospital. ＂lhe definite diagnosis was made after the surgery performed by our department, which was confirmed by pathological result. So far, there were few reports of giant cholesteatoma which occurs in fronto-parietal part ofskuU with bone defect.