江苏省启东市1993—2012年胃癌发病情况分析

Analysis of the incidence of gastric cancer in Qidong,Jiangsu Province from 1993 to 2012

目的分析江苏省启东市1993—2012年间胃癌的发病率,分析其危害程度及发病特征,为胃癌的预防、研究和控制工作的实施提供依据。方法整理启东市肿瘤登记处1993年1月至2012年12月启东市户籍人群胃癌发病资料,应用年均变化百分比(APC)模型分析启东胃癌发病率的时间变化趋势。采用2000年第五次全国人口普查的标准人口年龄构成进行标化。结果 1993—2012年间启东共报告胃癌新发病例8 272例,中位发病年龄为67.92(57.50~76.00)岁。其中,男性5 269例,中位发病年龄为67.25(57.75~74.75)岁;女性3 003例,中位发病年龄为69.16(57.00~77.91)岁。胃癌年均粗发病率为40.37/10万,标化发病率25.22/10万。1993—2002年间胃癌粗发病率呈明显下降趋势(APC=-1.59,t=-4.6,P<0.01),2002—2007年胃癌粗发病率呈明显著上升趋势(APC=8.88,t=-5.3,P<0.01)。1993—2002与2002—2007年间胃癌标化发病率与粗发病率趋势相同。男女性胃癌粗发病率均随年龄增长而上升(男:APC=734.8,t=-511.2,P<0.01;女:APC=43.6,t=17.9,P<0.01),在75~80岁人群中,男女性粗发病率均达到高峰。结论 1993—2012年启东市人群胃癌发病率较高,男性和老人是高发人群。

Objective To analyze the incidence of gastric cancer in Qidong,Jiangsu Province from1993 to 2012 and analyze the harmful levels and the clinical characteristics thereof,thus providing bases of implementing the prevention,research and control measures for gastric cancer. Methods The clinical data of gastric cancer from January 1993 to December 2012 for patients with census registration in Qidong were sorted out from the cancer registration center in Qidong. The annual percent change（ APC） model was used to analyze the trend over time for the incidence of gastric cancer. The incidence was standardized by utilizing the standard population age composition based on the nationwide census in 2000. Results A total of 8 272 new cases of gastric cancer were diagnosed in Qidong from 1993 to 2012,and the median age for these patients was 67. 92（ 57. 50-76. 00）. Among them,5 269 were male cases and the median age for these male patients was 67. 25（ 57. 75-74. 75）; 3 003 were female cases and the median age for these female patients was 69. 16（ 57. 00-77. 91）. The annual average for the crude incidence rate of gastric cancer was40. 37 /100 000,and the standardized incidence rate thereof was 25. 22. 37 /100 000. The crude incidence rate of gastric cancer decreased significantly from 1993 to 2002（ for the crude incidence rate thereof,APC =-1. 59,t =-4. 6,P〈0. 01）; the crude incidence rate of gastric cancer increased significantly from 2002 to 2007（ for the crude incidence rate thereof,APC =-8. 88,t =-5. 3,P〈0. 01）. Both the standardized incidence rate of gastric cancer and the crude incidence rate thereof had the same trend for the period from1993 to 2002 as well as the period from 2002 to 2007. The crude incidence rate of gastric cancer rose with the growth of ages（ for male patients,APC = 734. 8,t =-511. 2,P〈0. 01; for female patients,APC =43. 6,t = 17. 9,P〈0. 01）. The crude incidence rate of gastric cancer reached a climax for both males and females of the age group between 75 and 80. Conclusion The incidence of gastric cancer was relatively high in Qidong from 1993 to 2012; the male and the old-aged groups are high-risk groups.