早期鼻型结外NK／T细胞淋巴瘤治疗进展

Advances of treatment for early stage extranodal nature kiHer/T.cell lymphoma, nasal type

鼻型结外NK／T细胞淋巴瘤（ENKTL）是非霍奇淋巴瘤的一种特殊类型，具有侵袭性高、进展快、预后差等特性。好发于鼻腔，其中早期患者占多数，但治疗效果及预后不佳，目前尚缺乏标准治疗方案。近年来有研究报道含门冬酰胺酶的化疗方案治疗ENKTL可取得较好的近期疗效以及远期生存。本文将主要阐述早期鼻型结外NK／T细胞淋巴瘤的治疗新进展。

Extranodal natural killer/T-cell lymphoma （ENKTL） （nasal type） is a special type of non-Hodgkin lymphoma. This disease is highly aggressive with rapid progression and poor prognosis. It ap- pears mostly in nasal cavity, most patients are in early stage, and the treatment outcome and prognosis are poor. There is no standard treatment scheme. Recently, L-asparaginase based chemotherapy shows good short-term effect and long-term survival in the treatment of localized extranodal natural killer/T-cell lympho- ma. This review will explore the advances of treatment for localized extranodal nature killer/T-cell lympho-