经尿道双极等离子前列腺切除术治疗BPH继发OAB的疗效观察

Clinical observation of bipolar transurethral plasmakinetic prostatectomy in the treatment of overactive bladder secondary to BPH

目的:探讨经尿道双极等离子前列腺切除术对BPH继发膀胱过度活动症(OAB)的疗效。方法:收集2013年6月~2014年6月采用经尿道双极等离子前列腺切除术治疗的48例BPH继发OAB患者的临床资料,比较术前和术后3~6个月的国际前列腺症状评分(IPSS)、夜尿次数、储尿期症状评分、OABSS评分等指标的变化。结果:48例患者中,6例因术后OAB症状无缓解给予M受体拮抗剂。治疗前后(术后3个月)IPSS评分[(20.3±2.20)分vs.(8.1±3.0)分]、储尿期症状评分[(13.7±1.8)分vs.(6.1±1.9)分]、夜尿次数[(4.5±2.1)次vs.(2.1±1.2)次]、OABSS评分[(9.9±2.1)分vs.(5.3±1.7)分]的差异有统计学意义(均P<0.05),术后3个月储尿期症状评分和IPSS等改善明显,术后3~6个月仍会改善。结论:经尿道双极等离子前列腺切除术能有效地改善BPH继发OAB患者的症状,明显提高患者的生活质量。

Objective：To evaluate the efficacy of bipolar transurethral plasmakinetic prostatectomy for overactive bladder（OAB）secondary to BPH.Method：From June 2013 to June 2014 atotal of 48 patients diagnosed as OAB secondary to BPH were treateded by bipolar transurethral plasmakinetic prostatectomy.Clinical data of preoperative and postoperative 3-6months were compared and statistically analyzed,including IPSS,nocturia,the storage symptom score,residual urine volume and OABSS.Result：Six of them were given M-receptor antagonist.Significant improvement（P〈0.05）was noted in all the following parameters three months after treatment.The number of nocturia events decreased from（4.5±2.1）to（2.1±1.2）.IPSS decreased from（20.3±2.2）to（8.1±3.0）.The storage symptom score decreased from（13.7±1.8）to（6.1±1.9）.OABSS decreased from（9.9±2.1）to（5.3±1.7）.Conclusions：It is effective for patients with OAB secondary to BPH to accept bipolar transurethral plasmakinetic prostatectomy,and it can improve the quality of patients＇ life.