自血光量子疗法治疗急性颅脑损伤的临床效果

Clinical effect of autohemic ultraviolet therapy on acute craniocerebral injury

目的探讨自血光量子疗法治疗急性颅脑损伤的临床效果。方法选择2015年10月至2016年5月于武装警察部队后勤学院附属医院脑科中心收治的急性颅脑损伤患者120例，按随机数字表法分为对照组和观察组，各60例。对照组给予脱水降颅压、改善脑循环和营养支持等常规治疗，观察组在对照组的基础上加用自血光量子治疗，1次／d。2组均连续治疗7d。记录并比较2组患者治疗前后改良Rankin量表（mRS）评分、日常生活活动能力量表（Barthel指数）评分、血液流变学指标（包括血浆黏度、血细胞比容和红细胞沉降率）以及不良反应发生情况。结果对照组脱落5例，观察组脱落4例。治疗后，观察组mRS评分明显低于对照组[（2．8±0．5）分比（3．4±0．5）分]，Barthel指数评分明显高于对照组[（46±5）分比（38±7）分]，差异均有统计学意义（均P〈0．05）；观察组血浆黏度、血细胞比容、红细胞沉降率均明显低于对照组I（1．32±0．24）mPa·s比（1．63±0．30）mPa·s、（38±7）％比（41±6）％、（20±4）mm／1h比（22±3）mm／1h]，差异均有统计学意义（均P〈0．05）；观察组和对照组均未见不良反应。结论自血光量子疗法安全有效，能明显提高急性颅脑损伤患者的治疗效果。

Objective To explore the clinical effect of autohemic ultraviolet therapy on acute craniocere- bral injury. Methods A total of 120 patients with acute cranioeerebral injury from October 2015 to May 2016 in Brain Center, the Affiliated Hospital of Logistics University of Chinese People＇s Armed Police Force neurological hospital were randomly divided into control group and observation group, with 60 cases in each group. The control group had dehydration and nutritional support therapy; the observation group was added autohemic ultraviolet thera- py ; the treatment lasted for 7 d. Modified Rankin Scale （ mRS ） score, activities of daily living scale （ Barthel index） score, hemorheology indexes（plasma viscosity, hematoerit, erythrocyte sedimentation rate） and adverse reactions were analyzed. Results After treatment, the mRS score in observation group （55 cases available ） was significantly lower than that in control group（56 cases available） [ （2. 8 ±0. 5） scores vs （3.4 ±0. 5） scoresl （P 〈 0. 05 ） ; the Barthel score in observation group was significantly higher than that in control group [ （46 ± 5 ） scores vs （ 38± 7 ） scores ] （ P 〈 0. 05 ） ; plasma viscosity, hematocrit and erythrocyte sedimentation rates in observation group were significantly lower than those in control group [ （ 1.32 ± 0. 24） mPa· s vs （ 1.63 ± 0. 30） mPa ·s, （ 38 ± 7）% vs （41 ±6）%,（20±4）mm/1 h vs （22±3）mm/1 hi（P〈0.05）. No adverse reaction was observed in both groups. Conclusion Autohemic ultraviolet therapy is safe and effective for acute craniocerebral injury.