摘要
目前研究表明脂类在肠道微生物中的代谢可能与动脉粥样硬化相关，磷脂酰胆碱水平升高与心血管疾病的发生风险呈正相关，可能与磷脂酰胆碱在肠道菌群的作用下生成氧化三甲胺有密切关系。本文详细阐述了氧化三甲胺与心力衰竭、动脉粥样硬化和高血压等心血管疾病的关系。
The metabolism of lipid in intestinal microorganisms is related to atherosclerosis. High level of phosphatidylcholine is positively correlated with risk of cardiovascular diseases. Trimethylamine oxide is a metabo- lite of phosphatidylcholine with the action of intestinal bacteria; it may play a role in occurrence and development of cardiovascular diseases. This article explored relations among trimethylamine oxide, heart failure, atherosclero- sis and hypertension.
出处
《中国医药》
2017年第2期313-315,共3页
China Medicine
基金
首都医科大学基础临床合作研究基金（16JL34）
关键词
心血管疾病
磷脂酰胆碱类
氧化三甲胺
Cardiovascular diseases
Phosphatidylcholines
Trimethylamine oxide
