季节性和常年性中重度持续性变应性鼻炎患者生活质量对比研究

Comparative study on quality of life between the patients with seasonal and perennial moderate severe persistent allergic rhinitis

目的探讨季节性和常年性中重度持续性变应性鼻炎患者间的生活质量是否存在差异。方法将是否受季节影响的中重度持续性变应性鼻炎患者分为常年组和季节组,对比两组患者的生活质量评分以及变应原的种类和数量,分析所有患者致敏变应原数量与生活质量评分之间的相关性,并将两组致敏变应原的数量进行对比。结果季节组的生活质量评分要高于常年组,并有统计学意义,患者的生活质量评分与其致敏变应原的种类数量显著相关,数量越多,生活质量越差。季节组多种变应原致敏的患者所占的比例更大。结论季节性和常年性中重度持续性变应性鼻炎患者的生活质量存在差异,这可能与致敏变应原的种类、数量以及患者的耐受性有关。

OBJECTIVE To explore the differences in quality of life between the patients withseasonal and perennialmoderatesevere persistent allergic rhinitis.METHODS The patients with moderatesevere persistent allergic rhinitis were divided into two groups,seasonal group and perennial group.The distribution of allergens and the quality of life scores of the patients in the two groups were compared.The relationship between the quality of life and the number of allergens in all of the patients were analyzed.The number of allergens in two groups was compared.RESULTS The quality of life scores in seasonal group is higher than that of the perennial group with statistical significance.The patients＇ quality of life scores was significantly associated with the number of allergens.The seasonal group had a bigger proportion of patients with a variety of allergens.CONCLUSION There was a difference in the quality of life in patients with seasonal and perennial moderatesevere persistent allergic rhinitis.This may be related to the type of allergens,the quantity of allergens,and the patient＇s tolerance.