摘要
狼疮肾炎患者存在多种血清学的变化，其中包括补体类、自身抗体类、免疫球蛋白类和细胞因子等。这些物质不但参与了疾病的发生发展导致肾脏病理损害，同时也可作为生物标记物反映疾病变化。我们可通过监测血清学指标的变化诊断狼疮肾炎、判断病理分型、了解疾病活动性、评价治疗效果及预后，为狼疮肾炎早期诊疗提供科学依据。
There are a variety of serological changes in the blood circulation of patients with lupus nephritis, including complement, autoantibodies, immunoglobulin and cytokines and so on. These substances not only involved in the development of the disease leads to renal pathological damage, but also can be used as a biomarker to reflect changes in disease. In this paper, the detection of serum markers in lupus nephritis diagnosis, determine the pathological classification, disease activity, evaluation of therapeutic effect and prognosis were reviewed, in order to provide scientific basis for the early diagnosis and treatment of lupus nephritis by monitoring the changes of serum indicators.
作者
杨志鹏
刘红
王昌敏
Yang Zhipeng Liu Hong Wang Changmin(Clinical Laboratory Center, People ~s Hospital of Xinjiang Uygur Autonomous Region, Wulumuqi 830001, China)
出处
《中国综合临床》
2017年第1期83-87,共5页
Clinical Medicine of China
