莫沙比利与多潘立酮在消化不良治疗过程中的作用分析

Analysis of the Effect of Mosapride and Domperidone on the Treatment of Dyspepsia

目的比较莫沙比利与多潘立酮治疗消化不良的临床效果。方法将2014年1月—2015年12月在我院住院的155例功能性消化不良患者根据治疗药物不同分为多潘立酮组(65例)和莫沙必利组(90例),并比较两组患者临床治疗效果。结果多潘立酮组患者临床治疗总有效率与莫沙必利组比较差异具有统计学意义(P<0.05);多潘立酮组患者不良反应发生率与莫沙必利组比较差异无统计学意义(P>0.05)。结论与多潘立酮治疗比较,莫沙必利对功能性消化不良临床治疗效果更优,且不良反应轻微。

Objective To compare the clinical effects of mosapride and domperidone in the treatment of dyspepsia. Methods 155 patients with functional dyspepsia who were hospitalized in our hospital from January 2014 to December 2015 were divided into domperidone group（65 cases） and mosapride group（90 cases） according to the different therapeutic drugs. And compare the two groups of patients with clinical treatment. Results The total effective rate of the patients in the domperidone group was significantly different from the mosapride group（P〈0.05）. There was no significant difference in the adverse reaction rate between domperidone group and mosapride group（P〉0.05）. Conclusion Compared with domperidone treatment, mosapride clinical efficacy of functional dyspepsia better, and mild adverse reactions.