痰热清注射液治疗肾综合征出血热发热期患者的临床疗效

Clinical effect of tanreqing injection treated on fever period of hemorrhagic fever with renal syndrome

目的探讨痰热清注射液治疗肾综合征出血热(HFRS)发热期患者的临床疗效。方法选取本溪市第六人民医院2014年8月—2015年12月收治的HFRS发热期患者84例,随机分为对照组和治疗组,各42例。对照组患者给予利巴韦林+5%葡萄糖溶液,治疗组患者给予痰热清注射液+5%葡萄糖溶液;两组患者均持续治疗5 d。比较两组患者的临床疗效、症状消失时间及实验室指标恢复正常时间。结果治疗组患者治疗总有效率高于对照组(P<0.05)。治疗组患者皮肤黏膜停止出血、渗血停止、充血停止、退热时间短于对照组(P<0.05)。治疗组患者丙氨酸氨基转移酶(ALT)、肌酐(Cr)、尿素氮(BUN)、血小板计数、尿蛋白恢复正常时间短于对照组(P<0.05)。结论痰热清注射液治疗HFRS发热期患者临床疗效确切,可快速改善症状,加快实验室指标恢复速度。

Objective To investigate the clinical effect of tanreqing injection treated on fever period of hemorrhagic fever with renal syndrome（ HFRS）. Methods 84 cases of HFRS patients during fever period were selected from August 2014 to December 2015 in Benxi Sixth People＇s Hospital,which were randomly divided into control group and treatment group,42 cases in each group. Control group was given ribavirin ＋ 5% glucose solution,treatment group was given tanreqing injection ＋ 5%glucose solution. The clinical effect,symptoms disappear time and laboratory index normalization time were compared between the two groups. Results The total effective rate of treatment group was higher than control group（ P〈0. 05）. The time of skin and mucosa stopping bleeding, bleeding stopped, pump stopped and defervescence were shorter than control group（ P〈0. 05）. The normalization time of ALT,Cr,BUN,PLT,urine protein were shorter than control group（ P〈0. 05）. Conclusion Tanreqing injection treated on fever period of HFRS has a significantly clinical effect,it can quickly ease symptoms and speed up the laboratory indexes recovery.