尿液中分离大肠埃希菌及耐药性分析

目的对2639例尿液标本中分离到的大肠埃希菌进行耐药性监测统计分析，为临床更合理的使用抗生素提供参考。方法对2011年1月至2015年12月临床尿液标本中分离的大肠埃希菌体外药敏实验结果进行总结。结果研究显示大肠埃希菌每年所占尿液培养阳性标本的比例均〉30％，对常见抗菌药物的敏感性基本恒定且有上升趋势。结论临床应根据药敏试验，选择合适的药物，减少和降低菌株的耐药情况。

Objective To investigate the antimicrobial susceptibility of Escherichia coli isolated from urine samples collected from 2639 urine samples, and to provide reference for the clinical use of antibiotics. Methods The susceptibility test results of Escherichia coli isolated from clinical urine samples from January 2011 to December 2015 were summarized. Results The results showed that the proportion of positive specimens of urine culture was higher than 30%, and the susceptibility to common antimicrobial agents was basically constant and had an upward trend. Conclusions Clinical drug susceptibility test should be selected to reduce the drug resistance of the strains.