乳宁Ⅱ号方结合循经按摩对HER-2阳性乳腺癌术后康复效应的研究

Clinical Effect of "Runing Ⅱ" and Massage along Meridians Treatment on Patients with HER-2 Over-expressing Breast Cancer in Postoperative Rehabilitation Period

目的:评价中医药综合治疗对HER-2阳性乳腺癌患者术后康复期的疗效。方法:采用乳宁Ⅱ号方结合循经按摩佐间歇气压干预HER-2阳性乳腺癌术后患者,观察临床症状、乳腺增生结节、患肢淋巴水肿康复情况及无病生存期。结果:中医干预组治疗后41个临床症状改善;乳腺增生结节消失占14.47%,大部分消失占55.70%,部分消失占8.77%,无效占21.05%;患肢水肿腕上、肘横纹上下各10 cm周径数值治疗前后比较差异有统计学意义(P<0.05);无病生存期与对照组比较差异无统计学意义(P>0.05)。结论:中医药综合治疗对HER-2阳性乳腺癌术后康复期,在改善临床症状、乳腺增生结节、患肢淋巴水肿等方面疗效显著。

Objective：To evaluate the clinical efficacy of comprehensive therapy of Traditional Chinese Medicine on HER-2over-expressing breast cancer in postoperative rehabilitation period. Methods： ＂Runing Ⅱ＂,massage along meridians and intermittent pneumatic compression were used in the treatment of postoperative patients with HER-2 over-expressing breast cancer. The clinical symptoms,hyperplasia of mammary gland,upper extremity lymphedema,disease-free survival were observed. Results：The results showed that 41 types of common symptoms were improved. Hyperplasia of mammary gland was 14.47% disappeared,55.70% almost disappeared,8.77% disappeared partly,21.05% invalid. There was a significant difference in the arm circumference 10 cm above and10 cm below the wrist and cubital cease of the affected swollen limb before and after treatment（P〈0.05）. No difference was found between the two groups on disease-free surial（P〉0.05）. Conclusion：Combined treatment of Traditional Chinese Medicine for the treatment of postoperative HER-2 breast cancer patients has good curative effect in improving the clinical symptoms,hyperplasia of mammary gland,upper extremity lymphedema.