99Tcm-MDP骨显像肝脏异常显影原因分析

Analysis of abnormal liver uptake of 99Tcm-MDP in bone scan

目的 分析99Tcm-MDP全身骨显像肝脏异常显影的可能原因。方法 回顾性分析2013年1月至2015年7月于我院核医学科行99Tcm-MDP全身骨显像患者中肝脏异常显影20例，显像结果与其他影像学检查和（或）病理结果、实验室检查进行对比分析。结果 20例肝脏异常显影的患者中，原发性肝损伤3例、继发性肝损伤17例[其中包括多发性骨髓瘤引发肝功能异常1例，恶性肿瘤化疗后肝功能异常8例，肿瘤肝转移7例（结肠癌肝转移5例、肝癌肝内转移1例、肺癌肝转移1例）、慢性肾衰竭铁剂治疗后肝脏摄取1例]。结论 99Tcm-MDP全身骨显像肝脏异常显影的原因较多，除显像技术原因外，应警惕各种原因导致的肝脏损伤，为患者提前进行临床干预提供一定参考。

Objective To analyze the possible causes of liver uptake in 99Tcm-MDP bone scan. Methods A retrospective analysis was performed on 20 cases of abnormal liver uptake in bone scan in our hospital from January 2013 to July 2015. The results were compared with other imaging examinations and/or pathological findings and laboratory examinations. Results Twenty patients were found to have abnormal liver uptake of the imaging agent, including 3 cases with primary liver injury, 17 cases with secondary liver injury, which include 1 case with multiple myeloma and 7 cases with liver metastasis（5 cases with colorectal cancer, 1 with from hepatocellular carcinoma, 1 case with lung cancer）, and 1 case of liver uptake after iron treatment. Conclusion Abnormal liver uptake of 99Tcm-MDP in bone imaging is associated with several reasons; barring technical reasons, we should be alert to the liver injury caused by various reasons to provide reference for patients prior to clinical intervention.