期刊文献+

耐辐射奇球菌辐射抗性机制及其双组份系统的研究

The mechanism of resistance and two-component system in Deinococcus radiodurans
原文传递
导出
摘要 耐辐射奇球菌拥有极强的辐射抗性能力并能在多种极端环境下存活。其特有的一些辐射抗性基因在其抗性机制中发挥重要作用。双组份系统是广泛存在于细菌中的一种信号转导系统,它能协助细菌应对外界环境的变化,对维持各种生命活动至关重要。双组份系统作为一种应激响应机制在耐辐射奇球菌中有重要作用。笔者就耐辐射奇球菌的抗性机制及其双组份系统的研究进行综述。 Deinococcus radiodurans (DR) has strong resistance to radiation and comprises a series of mechanisms that allow it to survive under various extreme conditions. Some of the genes existing in DR particularly contribute to its robust viability. Two-component system (TCS) is a signal transduction system that widely exists in bacteria. This system can assist the bacteria in coping with the change in external environment and is vital for various life activities. Given that TCS plays an important role in resistance mechanism as a stress response system, this article reviewed the resistant mechanism and the TCS in DR.
出处 《国际放射医学核医学杂志》 2017年第1期45-49,共5页 International Journal of Radiation Medicine and Nuclear Medicine
基金 国家自然科学基金(81272993)
关键词 奇异珠菌属 辐射耐受性 双组份系统 Deinococcus Radiation tolerance Two-component system
  • 相关文献

参考文献2

二级参考文献16

  • 1Battista J R, EraL A M, Park M J. Why is Deinnococcus radiodurans so resistant to ionizing radiation[J]? Trends microbioL, 1999, 7:362-365.
  • 2Minton K W. DNA repair in the extremeLy radioresistant bacterium Deinnococcus radiodurans[J]. MOL MicrobioL, 1994, 13:9-15.
  • 3COX M M, Battista J R. Deinococcus radiodurans-the consummate survivor[J]. Nat Rev MicrobioL, 2005, 3: 882-892.
  • 4BLasius M, Sommer S, HUscher U. Deinococcus radiodurans: What belongs to the survival kit[J]? Crit Rev Biochem MoL BioL, 2008, 43:221-238.
  • 5Lange C C, Wackett L P, Minton K W, et al. Engineering a recombinant Deinococcus radiodurans for organopoLLutant degradation in radioactive mixed waste environment[J]. Nat BiotechnoL, 1998, 16(10): 929-933.
  • 6Xu W L, Shen J Y, Dumn C A, et al. The Nudix hydroLases of Deinococcus radurans[J]. Molecular Microbiology. 2001, 39(2): 286-290.
  • 7Gao G~ Tian B, Liu L, et al. Expression of deinococcus radiodttrans PprI enhances the radioresistance of Escherichia coli[J]. DNA Repair(Amst), 2003, 2(12): 1419-1427.
  • 8Hua Y J, Issay Narumi, Gao G J, et al. pprI: a generaL switch responsibLe extreme radioresistance of Deinococcus radiodurans[J]. Biophy Res Commun, 2003, 306:354-360.
  • 9Sheng D H, Liu R, Xu Z J, et al. DuaL negative reguLatory mechanisms of RecX on RecA functions in radiations resistance, DNA recombination and consequent genome instability in Deinococcus radiodurans[J]. DNA repair, 2005, 4(6): 671-678.
  • 10杨占山,李娜,王天昶.一种含有原核基凶pprI的真核重组质粒及其用途.国家发明专利,专利号:ZL200910003512.2,2011.4.6.

共引文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部