高压氧对迟发性放射损伤的作用

Hyperbaric oxygen therapy for delayed radiation injuries

放射疗法是一种对肿瘤和周围正常组织均有显著作用的物理疗法，在放疗的同时，不可避免地会损伤正常组织导致放射损伤，特别是迟发性放射损伤，这将严重影响患者的生存质量。随着时间的推移迟发性放射损伤会发展得更加严重，甚至致死，因此限制了临床治疗时的放射剂量，目前这一问题并未得到解决。笔者主要就高压氧治疗对迟发性放射损伤的影响作一综述。

Radiation therapy is a potent physical entity with dramatic effects in both malignant and surrounding normal tissues. Untoward reactions to radiation therapy in normal tissues are most frequently classified as either acute or delayed reactions. They are often progressive and serious and occasionally even lethal. These injuries effectively limit the clinical dose of radiation. This article mainly provides an overview of the use of hyperbaric oxygen therapy for delayed radiation injuries.