甲状腺功能亢进症合并骨质疏松症药物治疗的特殊性

The Specificity of the Treatment of Hyperthyroidism with Osteoporosis

甲亢和骨质疏松之间密切相关,严重和持久的甲亢必然会导致骨质疏松症。随着抗甲状腺药物和放射性碘用于治疗甲亢后,绝大多数甲亢患者的病情得以及时控制,从而显著减少了严重的骨质疏松症和骨折的出现。本文通过分析甲状腺相关激素对骨骼的调控作用,长期严重甲亢对骨密度和骨折的影响,以及亚临床甲亢对骨骼的长期影响,来阐述甲亢合并骨质疏松治疗的特殊性。

The close correlation between hyperthyroidism and osteoporosis, severe and persistent hyperthyroidism is bound to lead to osteoporosis. With the use of anti thyroid drugs and radioactive iodine for the treatment of hyperthyroidism, the severity of osteoporosis and fracture was improved in the vast majority of patients with hyperthyroidism and time control. Through analysis of the regulatory effect of thyroid hormone on bone, longterm effects of severe hyperthyroidism on bone density and fracture, and subclinical hyperthyroidism on the skeleton of the long-term effects, the particularity of hyperthyroidism with osteoporosis treatment was elaborated.