减重及代谢疾病病人围手术期静脉血栓栓塞症预防

Prevention of perioperative venous thromboembolism in patients with metabolic and bariatric surgery

减重手术已经成为治疗病态性肥胖的常用手段之一,其疗效确切。静脉血栓栓塞症(VTE)包括肺血栓栓塞症(PE)和深静脉血栓形成(DVT)为减重术后最为严重并发症及重要致死原因。诸如药物干预及机械辅助治疗手段被广泛应用于VTE的预防,而针对减重及代谢疾病病人围手术VTE预防的确切方案,尚存争议。相对而言,关于减重术后VTE的预防策略缺乏前瞻性随机研究。

Bariatric surgical procedure is one of the common methods of obesity treatment with established effectiveness now. Venous thromboembolism （VTE） events, which include deep vein thrombosis and pulmonary embolism, are the important sources of postoperative morbidity and mortality among bariatric surgery patients. Due to an understanding of the frequency and seriousness of those complications, bariatric surgery patients typically receive some method of VTE prophylaxis with lower extremity compression, pharmacologic prophylaxis, or both. However, the optimal approach in those patients is unclear. In contrast, the prevention of VTE after bariatric surgery is lack of prospective randomized study.