大黄保留灌肠预防ERCP术后PEP和高淀粉酶血症的护理体会

Nursing Experience Retention Enema of Daihuang in the Prevention of PEP and Hyperamylasemia after ERCP

目的:观察大黄保留灌肠对经内镜逆行性胰胆管造影术(ERCP)术后患者胰腺炎(PEP)及高淀粉酶血症发生率的影响。方法:方法:将需行ERCP检查及相关治疗的300例患者随机分为观察组、对照组各150例,观察组于ERCP术后给予大黄保留灌肠,对照组于ERCP术后给予生理盐水保留灌肠,观察2组血清淀粉酶水平及PEP发生率。结果:术后6小时血清淀粉酶水平异常率观察组为16.7%,对照组37.3%,2组比较差异有统计学意义(P<0.05);术后PEP发生率观察组为4.0%,对照组为6.0%,2组比较差异无统计学意义(P>0.05)。结论:ERCP术后应用大黄保留灌肠可有效降低ERCP术后血清淀粉酶水平。

Objective： To observe the effect of retention enema of Daihuang （Rheum polmatum.L）on the occurrence rate ofpancreatitis （PEP） and hyperamylasemia after ERCP. Methods： All 300 patients who need ERCP examination and the relevant treatment were randomly divided into the observation group and the control group, 150 cases in each group. The observation group was treated with retention enema of Daihuang after ERCP, and the control group was treated with normal saline retention enema. The serum amylase level and the occurrence rate of PEP of two groups were observed. Results： In six hours after surgery, the serum amylase level abnormal rate of the observation group was 16.7%, and the control group was 37.3%. There was significant difference between the two groups （P〈0.05）. The PEP occurrence rate of the observation group was 4.0% after surgery, and the control group was 6.0%, there was no significant difference between the two groups （P〉0.05）. Conclusion： Retention enema of Daihuangafter ERCP can effectively decrease the serum amylase level.