超声引导下甲状腺结节细针穿刺活检的临床应用价值

Clinical Values of Fine-needle Aspiration Biopsy in the Examination of Thyroid Nodules Guided by Ultrasound

目的:探讨超声引导下细针穿刺抽吸活检(US-FNAB)诊断甲状腺结节的准确性。方法:使用Bethesda系统标准对2014—2015年在甘肃省肿瘤医院就诊的240例甲状腺结节患者的穿刺结果进行分类。对照US-FNAB结果与术后组织病理结果,计算US FNAB的敏感性,特异性以及准确性。结果:经超声引导下细针穿刺活检,240个甲状腺结节中,良性86例,恶性69例,可疑恶性21例,涂片不满意7例。术后组织病理结果表明,240个甲状腺结节中,74例病理学结果为恶性,166例病理学结果为良性,220例细针穿刺活检结果与术后病理学结果相符,超声引导下甲状腺结节细针穿刺活检的敏感性为100%,特异性93.37%,准确性95.31%。结论:超声引导下细针穿刺活检对甲状腺结节诊断的可靠性强,能为临床治疗提供可靠依据。

Objective： To explore the accuracy of fine-needle aspiration biopsy in the examination of thyroid nodules guided by ultrasound. Methods： 240 cases had completed US FNAB in the examination of thyroid nodules in Gansu provincial cancer hospital from 2014 to 2015. Results were classified according to Bethesda system stan- dard. Compared the results of US FNAB with pathological results after surgery, sensitivity, specificity and accuracy of US FNAB were calculated. Results： After fine-needle aspiration biopsy guided by ultrasound, 86 benign cases, 69 malignant cases, suspicious malignancy 21 cases, unsatisfaction for smear 7 cases in 240 thyriod nodules. The results of tissue pathological after surgery, 74 cases were malignant, 166 cases were benign, the results of fine-needle aspi- ration biopsy of 220 cases were conformed to pathological results after surgery, sensitivity of fme-needle aspiration biopsy in the examination of thyroid nodules guided by ultrasound was 100.00%, specificity was 93.37%, accuracy was 95.31%. Conclusion： Fine-needle aspiration biopsy in the examination of thyroid nodules guided by ultrasound has high reliability, which can provide reliable basis for clinical doctors.