Masquelet技术治疗创伤后长骨骨髓炎的研究进展

Masquelet technique to treat post-traumatic osteomyelitis of long bones

创伤后长骨骨髓炎常继发于严重开放性骨折及部分闭合性骨折患者，一直以来都是临床骨科治疗的难题。Masquelet技术是近年来兴起的骨重建方法，在急性骨缺失、肿瘤、感染等方面的治疗都证实了其有效性。该技术主要分2期进行：一期通过彻底清创、抗生素骨水泥填充骨缺损控制感染，并诱导形成一层具有生物活性的膜；二期取出骨水泥，膜内植骨重建骨缺损。Masquelet技术使骨快速愈合以及重建大节段骨缺损的能力引起了越来越多的学者关注。本文就Masquelet技术治疗创伤后长骨骨髓炎的进展作一综述。

Long bone osteomyelitis often results from serious open fractures or some closed fractures. Its treatment is a clinical difficulty in orthopaedics. Masquelet is a new strategy for bone reconstruction, validated by surgeons in their treatment of acute bone loss, bone tumor and bone infection. It is carried out in 2 stages. At the first stage, infection was elinlinated by radical debridement and placement of antibiotic bone cement into the defect, which induces a pseudomembrane to facilitate the growth of bone graft. At the second stage, recon- struction of the bone defect is performed by bone grafting in the membrance after removal of the bone cement. The unique characteristics of this technique arouse more and more attention recently. Therefore, we would like to present a review about this Masquelet technique dealing with post-traumatic osteomyelitis of long bones.