我国儿童用药不良反应报告分析模式的文献计量分析

Pattern Research on the Analysis of Pediatric ADR Reports in China——Based on Bibliometrics and Bibliographic Informations of CNKI

目的:对我国儿童用药不良反应(ADR)报告分析模式进行初步探析。方法:从中国知网(CNKI)数据库检索并筛选出符合标准的文献183篇,分别提取关键字段建立数据库,分别从刊出情况(年刊出量、文献量比重、主要刊物分布)、来源情况(发文作者及合作情况、发文机构及合作情况、发文地区及行政等级分布)、内容分析(高频关键词分析、文献数据来源分析、文献主题分布)三个方面对我国儿童用药ADR报告分析类文献进行文献计量和题录信息分析。结果:我国儿童用药ADR报告分析的相关文献发文量逐年增长,且主要分布于药学类刊物,发文机构集中于医院,以机构内合作发文居多,发文主题以常规分析、抗菌药类药物分析和中药及类中药注射剂分析见长。结论:我国儿童ADR报告分析类研究有较大的提升空间,应加快推进我国儿童用药ADR基层监测及规范化建设,重视多中心合作,有效利用我国儿童ADR数据,以期今后在一定程度上减少儿童ADR的发生。

Objective：To research the pattern of the analysis of pediatric adverse drug reaction（ADR） reports in China. Methods：Literatures from CNKI Database were retrieved, compliant literatures were screened according to inclusion requirements, and bibliometric indicators were used to analyze by bibliometric metrology from three aspects： the publish- ment（ including the annual output, the literature quantity proportion and the distribution of major publications） , the source situation （ including the document authors and cooperation, the dispatch agencies and cooperation, the dispatch area and ad- ministrative level distribution）, the content situation（ including the high frequency keywords, the literature data sources and subject distributions of the literature） were included as well. Results：The number of the ducuments which about the analy- sis of pediatric ADR reports in China increased year by year, whom distributed in the pharmacy class publications, the post agencies focused on hospital especially with organizations teamed, the major subjects of documents were conventional analy- sis, antibiotic medicines analysis and Traditional Chinese medicine. Conclusion：There was still large room for improvement of the research on analysis of pediatric ADR reports in China, we should speed up the construction of ADR basic level mo- nitoring and standardization of children in our country, attach importance to the multi-center-cooperation, make an effective use of the pediatric ADR reports in China, in the hope of reducing the pediatric ADRs in the future.