超声检查在PCOS患者卵巢血流及子宫内膜厚度中的诊断价值

Diagnostic value of ultrasonography in detecting ovarian blood flow and endometrial thickness of PCOS patients

目的探析超声检查在多囊卵巢综合征(PCOS)患者的卵巢血流及子宫内膜厚度(ET)诊断中的临床应用价值。方法分析2014年4月至2016年9月在湖州市第一人民医院接受诊治的72例PCOS患者的临床资料。比较治疗前月经不同时期、治疗后促排卵成功与失败、妊娠成功与失败的PCOS患者的ET值及卵巢动脉血流情况。结果月经不同时期中PCOS患者的ET、左侧卵巢动脉血流RI值、右侧卵巢动脉血流RI值均无显著性差异(F值分别为0.566、0.664、0.790,均P>0.05)。72例PCOS患者接受促排卵治疗后,促排卵成功者62例,失败者10例。促排卵成功者注射h CG日与黄体中期的ET值均显著高于促排卵失败者(t值分别为3.143、4.284,均P<0.01),而卵巢动脉RI值则显著低于促排卵失败者(t值分别为21.11、17.14,均P<0.01)。62例促排卵成功的PCOS患者中,妊娠者30例,另外32例未妊娠,妊娠者注射h CG日ET明显高于未妊娠者(t=2.812,P<0.01),但两组注射h CG日卵巢动脉RI值无显著差异(t=1.118,P>0.05)。结论超声检查在PCOS患者的卵巢动脉血流及ET变化情况的检测工作中具有很高的应用价值,给PCOS疗效的预测及不孕症病因的探寻工作提供了有力、安全的依据,值得推广。

Objective To analyze the clinical application value of ultrasonography in diagnosing ovarian blood flow and endometrial thickness（ ET） of patients with polycystic ovary syndrome（ PCOS）. Methods Clinical data of 72 patients with PCOS receiving treatment at Huzhou First People＇s Hospital from April 2014 to September 2016 was retrospectively analyzed. ET and ovarian blood flow were detected by ultrasonography in patients with PCOS in different menstrual periods before treatment,in patients succeeded or failed in ovulation and in patients with successful or failed pregnancy after treatment. Results There were no significant differences in ET and left and right ovarian arterial blood flow RI values between PCOS patients in different menstrual periods（ F value was 0. 566,0. 664 and 0. 790,respectively,all P〉0. 05）. There were 62 PCOS patients with successful ovulation and 10 patients with unsuccessful ovulation after treated by ovulation induction. Values of ET at HCG injection day and midluteal phase in successful ovulation patients were obviously higher than those in unsuccessful ovulation patients（ t value was 3. 143 and 4. 284,respectively,both P〈0. 01）,but RI value of ovarian artery were obviously lower than those in unsuccessful ovulation patients（ t value was 21. 11 and 17. 14,respectively,both P〈0. 01）. There were 30 patients with successful pregnancy and 32 patients with unsuccessful pregnancy in 62 successful ovulation patients. Values of ET at HCG injection day in successful pregnancy patients were obviously higher than those in unsuccessful pregnancy patients（ t = 2. 812,P〈0. 01）,but RI values of ovarian artery at HCG injection day had no statistical difference（ t = 1. 118,P〉0. 05）. Conclusion Clinical application value of ultrasonography in detecting ET and ovarian blood flow of PCOS patients is very high,which provides a reliable and safety basis for prediction of therapeutic effect of PCOS and for exploration of infertility causes. It＇s worth promoting.