从“壮火”论糖皮质激素调节糖代谢作用机制

Effect of glucocorticoids on carbohydrate metabolism based on theory of “sthenic fire”

糖皮质激素(GC)是临床上作用广泛、机制复杂的常用药,对机体具有广泛的调节作用,并随剂量不同表现出不同的作用。中医学提出"壮火之气衰,少火之气壮""壮火食气",从中医"壮火"理论探究应用GC非基因调控途径糖代谢作用机制,以达到在中西医结合理论指导下实现糖皮质激素的合理应用的目的。

Glucocorticoid is widely used in clinic, which has a wide range of regulatory effects on the body, and has different effects on the different doses. Chinese medicine puts forward ＂qi decline of zhuang huo, less fire fierce＂ ＂Zhuang fire fresh air ＂, from TCM＂ Zhuang huo ＂theory to explore on the application of GC gene regulation of glucose metabolism mechanism, to achieve in traditional Chinese and western medicine combined with GC under the guidance of the theory of reasonable application.