角膜滞后量在青光眼诊断和治疗中的应用价值

Application value of corneal hysteresis in diagnosis and treatment of glaucoma

青光眼是全球首位不可逆致盲性眼病，其发病机制尚不完全清楚。角膜与巩膜的胶原纤维互相连接延续且二者具有相似的细胞外基质成分，视神经筛板处的生物力学特征可能与角膜的生物力学特性相关，因此青光眼患者角膜的生理功能变化可以间接反应筛板处受压及损伤情况。近年来测量角膜滞后量的技术方法不断更新，许多研究结果显示低角膜滞后量与青光眼及其发展进程相关，这更新了学界对角膜与青光眼之间关系的认识。本文对角膜滞后量的特性、检查方法及其与青光眼的关系进行综述，以期为临床工作提供参考。

Glaucoma is the first leading cause of irreversible blindness world widely, but the pathogenesis was still unclear. The collagen fibers from cornea and sclera connect to each other and both of them have similar extraeellular matrix components. The biomeehanieal characteristics of optic nerve lamina cribrosa may associated with the biomeehanical properties of the cornea. Therefore, the study of corneal physiological can indirectly reflex the compression and damage in optic nerve lamina cribrosa. The technical developments in corneal hysteresis examination had been updated these years constantly. Many researches implicated that low corneal hysteresis involved in pathogenesis and progression of glaucoma which refresh our recognition of the relationship between cornea and glaucoma. This review summarized the characteristics of corneal hysteresis, the examination and the connection with glaucoma to provide the reference for clinical work.