依达拉奉联合醒脑静治疗急性脑梗死的疗效观察

Observation of curative effect by edaravone combined with Xingnaojing in the treatment of acute cerebral infarction

目的分析对急性脑梗死患者采用依拉达奉联合醒脑静治疗的临床疗效。方法 100例急性脑梗死患者,随机分为对照组和观察组,各50例。对照组采用醒脑静治疗,观察组在对照组基础上采用依达拉奉治疗,比较两组治疗效果及神经功能情况。结果研究中观察组显效30例,有效18例,无效2例,总有效率为96%;对照组显效19例,有效22例,无效9例,总有效率为82%;两组总有效率比较差异有统计学意义(χ2=5.0051,P<0.05)。观察组患者神经功能缺损评分为(7.52±3.24)分,明显低于对照组的(14.85±4.59)分,差异有统计学意义(t=9.2253,P=0.0000<0.05)。结论采用依达拉奉联合醒脑静治疗急性脑梗死患者可起到更好的临床疗效,有极高应用价值。

Objective To analyze clinical effect by edaravone combined with Xingnaojing in the treatment of acute cerebral infarction patients. Methods A total of 100 patients with acute cerebral infarction were randomly divided into control group and observation group, with 50 cases in each group. The control group received Xingnaojing for treatment, and the observation group also received additional edaravone for treatment. Curative effects and neurological function status were compared between the two groups. Results There were 30 excellent cases, 18 effective cases and 2 ineffective cases in the observation group, with total effective rate as 96%. There were 19 excellent cases, 22 effective cases and 9 ineffective cases in the control group, with total effectiverate as 82%. The difference of total effective rate had statistical significance between the two groups（χ^2=5.0051, P〈0.05）. The observation group had obviously lower neurological functional deficit score as（7.52±3.24） points than（14.85±4.59） points in the control group, and their difference had statistical significance（t=9.2253, P=0.00000.05）. Conclusion Implement of edaravone combined with Xingnaojing provides excellent clinical effect in the treatment of acute cerebral infarction patients, and this method contains high value of application.