不同年龄组肝癌患者经导管肝动脉化疗栓塞术后生存状况的比较分析

Living situations of PHC patients of different age groups after TACE transcatheter arterial chemoembolization

目的探讨经导管肝动脉化疗栓塞术后不同年龄组肝癌患者生存状况的差异,为临床进行干预提供依据。方法采用方便抽样方法抽取苏州某三甲医院在2014年5月-2015年5月153例住院的行肝动脉化疗栓塞术后的肝癌患者进行调查,比较青年组、中年组和老年组肝癌患者的一般资料、抑郁情绪、生活质量、症状负担以及社会支持情况。结果不同年龄组患者在文化程度、婚姻状况、职业、人均收入、家庭类型、有无接受健康培训、(alpha fetoprotein,AFP)是否异常、体能评分等有差异(均P<0.05);不同年龄组肝癌患者TACE术后抑郁情绪、生活质量、症状负担和社会支持方面有差异。进一步两两比较,其中抑郁程度中年组高于老年组;生活质量青年组高于中年组,老年组高于中年组;症状负担青年组高于老年组,中年组高于老年组;社会支持青年组高于老年组,中年组高于老年组(均P<0.05)。结论不同年龄组的肝动脉化疗栓塞术后肝癌患者的生存状况具有差异,医护人员应重视其差异从而实施有针对性的干预措施。

Objective To explore the living situations of primary hepatic carcinoma（PHC） patients of different ages after transcatheter arterial chemoembolization（TACE）. Methods By convenience sampling, 153 PHC patients after TACE were enrolled from a Glass 1 Grade A hospital. Their data were collected with general data questionnaire, Zung ＇s SDS scale, quality of life cancer（QOL-LC）, memorial symptom assessment scales and social support scale to investigate the PHC patients. Results The differences were statistically significant in view of cultural level, marriage status, occupation, state of the economy, family type, preoperative health training, AFP（alpha fetoprotein）, and physical stamina score（all P0.05）. Among the groups of different ages, there were also statistically significant differences in terms of depression, life quality, symptom burdens and social support. More exactly, the level of depression in the group of middle age was significantly higher than that of the group of old age; The symptom burdens of the group of young age and middle age were higher than those of the group of old age. The social support and life quality of the groups of young age and middle age was both higher than that of the group of old age（all P〈0.05）. Conclusions The living situations of PHC patients of different ages after TACE are different. Doctors and nurses should consider the differences in their depression, quality of life, and social support so as to take pertinent interventions.