越橘叶黄素酯β-胡萝卜素软胶囊生产工艺及其质量控制点

Production process and its quality control points of cranberry-lutein ester-beta carotene soft capsule

本文简单介绍了越橘叶黄素酯β-胡萝卜素软胶囊其中的花色素苷、叶黄素、β-胡萝卜素这3个主要成分的作用,该软胶囊具有显著缓解视疲劳的功能。简要论述了越橘叶黄素酯β-胡萝卜素软胶囊生产工艺流程中的化胶、配料、压丸、干燥、灯检和包装这6个工序的主要操作及其操作要点。该软胶囊产品生产的关键控制因素有内容物颗粒度、温度和湿度。此产品中的3个功效成分的主要影响因素有温度、湿度、光照、pH值和空气,围绕这5个影响因素结合软胶囊的生产过程对生产的关键控制因素进行改善,改善结果为：内容物温度控制在40℃、内容物充氮气保存和产品干燥水分控制在7%~15%。加速实验表明,改善后产品中花色素苷和叶黄素酯的含量有相对稳定的趋势。

ABSTRACT：This paper introduced the function of 3 major components （anthocyanins, lutein and beta carotene） of the cranberry-lutein ester-beta carotene soft capsule which had the function of relieving visual fatigue. The main operation and points of 6 processes of the soft capsule were briefly discussed including gelation, mixing, pressing pill, drying, light inspection and packaging. The key controlling factors of production of the soft capsule were the particle size of content, temperature and humidity. The 3 function components of this product were mainly affected by temperature, humidity, light, pH value and air. The improvement of the key controlling factors of production were conducted around the above 4 factors combined with the production process of soft capsule, and the results were as follows： the temperature of content was 40℃,nitrogen storage and drying moisture of the product was 7%~15%. Accelerated experiments showed that there was a relatively stable trend of the content of anthocyanins and lutein esters in soft capsule after the improvement.