摘要
失血性休克(hemorrhage shock,HS)动物模型应用广泛,是阐明致病机制,研发止血材料,检验应急救护设备,筛选复苏用药的重要平台。该文综述了国内外报道的常用失血性休克动物模型,重点阐述了动物选择、模型创建、影响因素和适用范围等内容,力争为科研和医务工作者在模型选择与应用方面提供有益参考。
An animal model of hemorrhagic shock is widely applied. It is an important platform to clarify the pathogenic mechanism, develop hemostasis materials, test first aid equipments and filter resuscitation medications. This paper summa- rizes the commonly used animal models of hemorrhagic shock at home and abroad, focusing on animal selection, model cre- ation, influencing factors, and fields of application in order to provide useful reference for model selection and application by medical practitioners and researchers.
出处
《军事医学》
CAS
CSCD
北大核心
2017年第1期73-76,共4页
Military Medical Sciences
基金
国家重大专项重大新药创制资助项目(2012ZX09102301-017)
关键词
失血性休克
大出血
模型
动物
损伤模式
影响因素
hemorrhage shock
massive hemorrhage
models
animal
damage patterns
influence factors
