摘要
老年卵巢癌是指年龄大于65岁女性的卵巢癌。近半数(45%)的患者在诊断时大于64岁。随着人口老龄化和预期寿命的提高,老年卵巢癌患者的比例将会进一步增加,由于治疗并发症和毒副反应,老年患者多未接受标准治疗(满意的肿瘤细胞减灭术和以铂类为基础的联合化疗),因此老年卵巢癌的生存率没有提高甚至出现下降。对大部分老年卵巢癌患者实施标准治疗是可行的。为了提供最佳的治疗方案,治疗前的评估是必要的。另外,还需对老年卵巢癌患者进行前瞻性研究,以期为老年卵巢癌患者是否能从治疗中获益提供证据。
Epithelial ovarian cancer is a cancer of older women. Nealy half（45%） of women diagnosed with ovarian cancer would be older than 64 years old. This ratio is expected to increase in the coming decades for the aging population and improving life-expectancy. But most of the older women with ovarian cancer did not receive standard treatment because of the complication and toxic and adverse effects, which leaded to the worse survival rate. The majority of elderly patients are able to tolerate the standard care for ovarian cancer including initial surgical cytoreduction followed by platinum and taxane chemotherapy. To offer optimal radical management,pretreatment assessment is necessary. Large prospective clinical trials for elderly patients with ovarian cancer could offer justified evidence weather they could be benefited from the treatment.
出处
《国际妇产科学杂志》
CAS
2017年第1期13-17,共5页
Journal of International Obstetrics and Gynecology
关键词
卵巢肿瘤
老年人
药物疗法
联合
治疗前评估
Ovarian neoplasms
Aged
Drug therapy
combination
Pretreatment assessment
