功能化氧化石墨烯作为药物载体材料的研究进展

Research progress on functionalized graphene oxide as drug carriers

功能化氧化石墨烯基于石墨烯的结构改造得到,具有良好的水溶性、生物相容性、较高的载药率以及易于修饰等优点,在国内外引起广泛的关注。本文综述了氧化石墨烯的表面修饰,以及它作为药物递送载体在抗肿瘤、抗菌、高血压治疗、基因治疗以及生物安全性评价等方面的应用,为其在生物医药领域的应用提供新方法和新思路。

Functionalized graphene oxide is prepared based on graphene.It has attracted great interest from all over the world due to its good solubility,biocompatibility,high loading rate,and easy modification.This paper summarizes the surface modification of graphene oxide,and its applications on anti-tumor,antibacteria,antihypertension,gene therapy and biosafety as a drug carrier,providing new methods and ideas in the biomedical field.