石墨烯量子点磁性复合纳米粒子分散固相微萃取-毛细管电泳法测定肉桂酸及其衍生物

Determination of cinnamic acid and its derivatives by dispersive solid phase microextraction of graphene quantum dots magnetic composite nanoparticles coupled with capillary electrophoresis

通过一步化学共沉淀法制备了石墨烯量子点(graphene quantum dots,GQDs)包覆的Fe3O4磁性纳米复合材料(Fe3O4-GQDs),并将其用于肉桂酸及其衍生物(肉桂酸、3,4-二甲氧基肉桂酸、4-甲氧基肉桂酸、阿魏酸、反-4-羟基肉桂酸)的固相微萃取,并与毛细管电泳联用建立了测定肉桂酸及其衍生物的新方法。实验考察了吸附溶液的pH值、吸附时间、吸附剂用量、脱附时间等因素对萃取效率的影响。实现了肉桂酸及其衍生物的快速高效富集和高灵敏度检测,加标回收率为86.2%~96.2%,相对标准偏差为1.8%~4.3%。结果表明,合成的Fe3O4-GQDs磁性纳米粒子可作为一种良好的吸附材料应用于特定样品的富集。

Composites of graphene quantum dots （GQDs） and Fe3O4 （ Fe3O4-GQDs） nanoparti-cles were prepared via a one-step co-precipitation approach. And the synthesized Fe3O4-GQDs nanoparticles were applied to the extraction of five compounds of cinnamic acid and its deriva-tives （cinnamic acid,3,4-dimethoxycinnamic acid,4-methoxycinnamic acid,ferulic acid and trans-4-hydroxycinnamic acid）. Cinnamic acid and its derivatives were detected by capillary electrophoresis （CE）. The pH of adsorption solution,adsorption time,amount of adsorbent and desorption time were investigated. The rapid and efficient preconcentration of the five cin-namic acid and its derivatives was successfully obtained with the satisfactory recoveries of 86.2%-96.2%,and relative standard deviations of 1.8%-4.3%. The results indicated that Fe3 O4- GQDs magnetic nanoparticles were good pretreatment alternatives.