遗忘型与血管性轻度认知功能障碍患者认知缺损特征的比较与分析

Comparison and Analysis of the Characteristics between the Patients with aMCI and the Patients with vMCI

目的分析遗忘型轻度认知功能障碍(amnestic mild cognitive impairment,aMCI)和血管性轻度认知功能障碍(vascular mild cognitive impairment,vMCI)患者认知缺损的特征。方法选取41例老年aMCI患者和38例老年vMCI患者,采用简易精神状态检查量表、蒙特利尔认知评估量表(Montreal cognitive assessment scale,MoCA)和老年成套神经心理测验(neuropsychological test battery,NTB)评估患者的认知功能。结果 MoCA分测验中,vMCI患者的延迟回忆得分低于aMCI患者(0.95vs1.83,P<0.05)。NTB分测验中,vMCI患者的听觉词语-延迟回忆1得分低于aMCI患者[(2.86±3.27)vs(5.89±4.27),P<0.05]。结论与aMCI患者相比,vMCI患者听觉词语-延迟回忆的损伤更为严重,听觉词语-延迟回忆测验或许可以成为区分vMCI和aMCI的工具。

Objective To analyze the characteristics of cognitive impairment of the patients with amnestic mild cog-nitive impairment （aMCI） and the patients with vascular mild cognitive impairment （vMCI）. Methods 41 patients with aMCI and 38 patients with vMCI were selected and Mini Mental State Examination （MMSE）, Montreal Cognitive Assessment Scale （MoCA） and Neuropsychological Test Battery （NTB） were applied in assessing the cognitive function of all the patients. Results There existed a statistical difference in auditory verbal learning test between the patients with aMCI and the patients with vMCI, MoCA （0.95 1.83, P〈0.05） and NTB [（2,86±3.27） ra （5.89±4.27）,P 〈 0 .0 5 ] . Conclusions Theimpairment of auditory verbal-delayed recall in patients with vMCI is more severe than that in patients with aMCI, which may be taken as a tool to distinguish vMCI from aMCI.