不同药物组合雾化吸入治疗小儿喘息性支气管炎的效果

Effect of different drug combination aerosol inhalation in the treatment of pediatric asthmatic bronchitis

目的比较吸入用布地奈德混悬液分别与硫酸特布他林雾化液、吸入用复方异丙托溴铵溶液联合雾化吸入治疗小儿喘息性支气管炎的效果。方法选取我院2013年1月~2016年8月收治的喘息性支气管炎患儿80例,随机分为A组和B组,各40例。A组患儿予布地奈德联合特布他林雾化吸入治疗;B组予布地奈德联合复方异丙托溴铵雾化吸入治疗,对比两组喘息性支气管炎患儿治疗效果。结果 A组的有效率为97.5%,与B组的95.0%相当,差异无统计学意义(P>0.05)。两组治疗后咳嗽、喘息及肺部体征改善时间比较,差异无统计学意义(P>0.05)。结论在小儿喘息性支气管炎的临床治疗中,应用吸入用布地奈德混悬液分别与硫酸特布他林雾化液、吸入用复方异丙托溴铵溶液联合雾化吸入治疗法,均能够明显改善患儿的临床症状,取得比较好的临床效果,值得临床推广应用。

Objective To compare the efficacy of combination aerosol inhalation of Budesonide Suspension combined with nebulized inhalation of Terbutaline Sulfate,Compound Ipratropium Bromide Solution for Inhalation in the treatment of pediatric asthmatic bronchitis.Methods Eighty children with asthmatic bronchitis in our hospital from January 2013 to August 2016 were randomly selected,and they were divided into group A and group B,with 40 patients in each group. Group A was given aerosol inhalation of Budesonide combined with Terbutaline;group B was given aerosol inhalation of Budesonide combined with Compound Ipratropium Bromide Solution for Inhalation.The therapeutic effect of asthmatic bronchitis was compared between two groups.Results The therapeutic effect of the group A （97.5%） was similar to that of the group B （95.0%）,and the difference was not statistically significant （P〉0.05）.The improved time comparison of cough,wheeze and lung signs after treatment of the two groups had no statistically significant difference （P〉0.05）.Conclusion In the clinical treatment of pediatric asthmatic bronchitis,combination aerosol inhalation of inhaled Budesonide Suspension combined with aerosol solution of Terbutaline Sulfate,Compound Ipratropium Bromide Solution for Inhalation can significantly improve the clinical symptoms of children,which achieves better clinical effect and it is worthy of clinical promotion and application.