贫血程度及持续时间对重型颅脑损伤预后的影响

Effect of anemia on the prognoses in patients with severe traumatic brain injury

目的探讨重型颅脑损伤(TBI)患者伤后7 d内贫血的程度和持续时间对其预后的影响。方法 2012年6月至2016年2月收治符合入选标准的重型TBI 91例,以血红蛋白浓度(Hb)等于90 g/L作为分组的标准阈值分为Hb<90 g/L组(61例)和Hb≥90 g/L组(30例),以贫血面积参数(AAI)、GOS评分和KPS评分等作为主要观察指标。结果出院后6个月,Hb≥90 g/L组GOS评分[(4.4±1.1)分]和KPS评分[(83.7±26.2)分]均明显高于Hb<90 g/L组[分别为(3.3±1.0)分、(57.7±24.4)分;P<0.05]。Hb<90 g/L组患者AAI与GOS、KPS评分均呈显著负相关(rs分别为-0.705,-0.702;P<0.01)。结论 TBI患者在伤后7 d Hb<90 g/L及其持续时间与患者预后密切相关,Hb≥90 g/L有利于改善患者预后。

Objective To explore the effects of anemia within 7 days after the injury on the prognoses in the patients with severe traumatic brain injury （TBI）. Method Of 91 patients with severe TBI treated in our hospital from June, 2012 to February, 2016, 61 had anemia ]hemoglobin （Hb） concentration 〈90 g/L] and 31 did not （Hb〉90 g/L）. The main observed indexes were anemia area index （AAI）, GOS score and Karnofsky performance scale （KPS） score. The relationship among them was analyzed. Results The GOS score [（4.433±1.073） points] and KPS score [（83.667±26.193） points] were significantly higher in the patients without anemia than those [（3.328±0.978） points and [（57.704±24.385） points respectively] in the patients with anemia （P〈0.05）. Conclusions The degree and duration of anemia （Hb〈90 g/L） is closely related to the prognoses in the patients with severe TBI. Hb≥90 g/L is helpful to improving the prognoses in patients with severe TBI.