卡前列素氨丁三醇用于剖宫产术中宫缩乏力的临床效果

Explore the Curative Effects of Carboprost Tromethamine Used for Uterine Atony in Cesarean Section

目的:观察卡前列素氨丁三醇用于治疗剖宫产术中宫缩乏力的临床效果。方法:随机选取2014年3月-2016年5月笔者所在医院剖宫产术中出现子宫收缩乏力的患者86例,随机分为观察组及对照组,每组43例。观察组应用卡前列素氨丁三醇,对照组应用缩宫素。观察两组临床疗效、术中及术后2、24 h出血量、药物不良反应。结果:观察组临床疗效明显优于对照组,两组比较差异有统计学意义(P<0.05);观察组术中及术后2、24 h出血量均低于对照组,两组比较差异有统计学意义(P<0.05);两组均未见明显不良反应,两组相比差异无统计学意义(P>0.05)。结论:卡前列素氨丁三醇对于治疗剖宫产术中子宫收缩乏力所致产后出血效果明显,值得临床推广应用。

Objective： To explore the curative effects of Carboprost Tromethamine used for uterine atony in cesarean section.Method： From March 2014 to May 2016, eighty-six patients with uterine atony in cesarean section in the hospital were selected and randomly divided into the observation group and the contrast group.Each group had forty-three cases.Patients in the observation group were injected with Carboprost Tromethamine.Patiants in the contrast group were injected with Oxytocin.The curative effects, the amount of intraoperatlve hemorrhage, postpartum hemorrhage at two hours, twenty-four hours after operation, and drumadverse reaction were observed.Result： The curative effects of the patients in observation group was better than the contrast group.The difference between two groups was statistically significant（P〈0.05）.The amount of intraoperative hemorrhage, postpartum hemorrhage at two hours and twenty-four hours after operation of the patients in observation group were lower than those in contrast group.The difference between two groups was statistically significant（P〈0.05）.There was no obvious drug adverse reaction in two groups.The difference between two groups was not statistically significant（P〉0.05）.Conclusion： The curative effects of Carboprost Tromethamine used for postpartum hemorrhage caused by uterine atony in cesarean section are significant.It＇s worthwhile to further its application.