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Researchers Reveal the Molecular Basis of the Broad Neutralizing Activity of Human Antibody 3E1 against Influenza A Viruses

Researchers Reveal the Molecular Basis of the Broad Neutralizing Activity of Human Antibody 3E1 against Influenza A Viruses
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摘要 On Dec.2^(nd),2016,a joint team revealed online in Nature Communications that 3E1 could neutralize H1 and H5 subtype viruses by targeting a conserved and unique epitope on hemagglutinin(HA)stem region,hence inhibiting low pH-induced HA conformational change and blocking membrane fusion. On Dec.2^nd,2016,a joint team revealed online in Nature Communications that 3E1 could neutralize H1 and H5 subtype viruses by targeting a conserved and unique epitope on hemagglutinin(HA)stem region,hence inhibiting low pH-induced HA conformational change and blocking membrane fusion.
出处 《Bulletin of the Chinese Academy of Sciences》 2016年第4期245-246,共2页 中国科学院院刊(英文版)
基金 supported by grants from the National Natural Science Foundation of China and CAS
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