右美托咪定在腹腔镜手术麻醉中的应用效果

Application effect of dexmedetomidine in laparoscopic surgery anesthesia

目的观察和分析右美托咪定在腹腔镜手术麻醉中的应用效果。方法 80例行腹腔镜手术的患者,随机分成实验组和对照组,每组40例。对照组患者给予麻醉用药丙泊酚治疗,实验组选择右美托咪定治疗。对比两组患者的麻醉效果和不良反应。结果实验组拔管时间(11.18±4.64)min、清醒时间(7.39±2.22)min优于对照组(23.02±10.21)、(17.30±7.43)min,差异具有统计学意义(P<0.05)。实验组中无术后疼痛,恶心呕吐1例,对照组中术后疼痛40例(100.0%),恶心呕吐6例(15.0%),两组比较差异具有统计学意义(P<0.05)。结论腹腔镜手术患者在麻醉过程中,右美托咪定麻醉时拔管时间、不良反应、清醒时间均优于丙泊酚麻醉方法 ,可以有效缓解患者的病情,值得参考。

Objective To observe and analyze application effect of dexmedetomidine in laparoscopic surgery anesthesia. Methods A total of laparoscopic surgery patients were randomly divided into experimental group and control group, with 40 cases in each group. The control group received propofol for anesthesia, and the experimental group received dexmedetomidine for anesthesia. Comparison were made on anesthesia effect and adverse reactions. Results The experimental group had extubation time as （11.18 ± 4.64）min, sober up time as （7.39 ± 2.22）min, which were all better than （23.02 ± 10.21） and （17.30 ± 7.43）min in the control group, and their differences had statistical significance （P〈0.05）. The experimental group had 0 case, 1 nausea and vomiting case, while the control group had 40 postoperative pain cases （100.0%）, 6 nausea and vomiting cases （15.0%）. There were statistically significant differences in two groups （P〈0.05）. Conclusion Implement of dexmedetomidine for anesthesia shows better extubation time, adverse reactions and sober up time than propofol for anesthesia in laparoscopic surgery patients, which can effectively relive state of illness. So this method is worthy of reference.