典必殊滴眼液联合非甾体类抗炎药应用于白内障术后疗效及护理对策

Curative effect of tobradex eyedrops combined with non-steroid anti-inflammatory drugs for the treatment of postoperative cataract and its nursing measures

目的分析白内障术后应用妥布霉素地塞米松滴眼液(典必殊滴眼液)联合非甾体类抗炎药时的护理方法和效果。方法 80例行白内障手术的患者,随机分为观察组和对照组,各40例。对照组患者采用典必殊滴眼液治疗并实施常规护理,观察组患者在对照组基础上加用非甾体抗炎药治疗并给予针对性护理干预。比较两组治疗效果。结果观察组显效30例,有效7例,无效3例,总有效率为92.5%;对照组显效12例,有效18例,无效10例,总有效率为75.0%;两组总有效率比较差异有统计学意义(P<0.05)。观察组发生恶心呕吐1例(2.5%),头痛0例,腹痛1例(2.5%),并发症发生率为5.0%;对照组发生恶心呕吐3例(7.5%),头痛2例(5.0%),腹痛3例(7.5%),并发症发生率为20.0%;两组并发症发生率比较,差异有统计学意义(P<0.05)。术后14、30 d,观察组眼压明显低于对照组,差异有统计学意义(P<0.05)。结论对白内障术后患者实施典必殊滴眼液联合非甾体抗炎眼液治疗时,通过在常规护理基础上实施针对性护理能够明显改善治疗效果,并可提升治疗安全性,有着较高的临床应用价值。

Objective To analyze nursing methods of tobramycin and dexamethasone eye drops （tobradex eyedrops） combined with non-steroid anti-inflammatory drugs for the treatment of postoperative cataract and their effect. Methods A total of 80 patients received cataract operation were randomly divided into observation group and control group, with 40 cases in each group. The control group received tobradex eyedrops for treatment and conventional nursing, and the observation group also received anti-inflammatory drugs for treatment and targeted nursing intervention. Curative effect was compared in two groups. Results The observation group had 30 excellent cases, 7 effective cases and 3 ineffective cases, with total effective rate as 92.5%. The control group had 12 excellent cases, 18 effective cases and 10 ineffective cases, with total effective rate as 75.0%. There was statistically significant difference in total effective rate in two groups（P〈0.05）. The observation group had 1 nausea and vomiting case （2.5%）, 0 headache case, 1 stomach case （2.5%）, with incidence of complications as 5.0%, while the control group had 3 nausea and vomiting cases （7.5%）, 2 headache cases （5.0%）, 3 stomach cases （7.5%）, with incidence of complications as 20.0%. There was statistically significant difference in incidence of complications in two groups （P〈0.05）. The observation group had clearly lower intraocular pressure than the control group in postoperative 14 and 30 d, and the difference had statistical significance （P〈0.05）. Conclusion For postoperative cataract patients treated with tobradex eyedrops combined with non-steroid anti-inflammatory drugs, conventional nursing combined target nursing can clearly improve therapeutic effect, and promote treatment security. So this method contains high clinical application value.